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Weight loss poses a huge challenge for most people who attempt it.

What role, if any, does a person’s gut microbiome play in how easy or difficult it can be to lose weight?

A recent study looked at the microbiomes of people who lost weight and compared them to the microbiomes of people who did not lose weight . . . and researchers found some interesting links!

People who were able to lose weight had more microbes that grew faster and produced anti-inflammatory compounds, while those who did not lose weight had more microbes that produced the enzyme amylase that breaks starches into sugars.

Introducing a done-for-you pre-written Health scoop (new study update) to share this information with your clients and patients along with a few practical tips.

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Product Details:

Document Type: MS Word

Release Date: November 2021

Categories: Health scoop (new study updates), Health goals news, Foods & diet news

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Effortlessly send your email subscribers updated new health information with practical tips each week without having to decide on a topic and create something brand new from scratch.

This Health scoop (new study update) was created to help you consistently stay in touch with your email subscribers while keeping you up-to-date with some of the most fascinating recent studies and includes:

A short primer for your clients on the gut microbiome and that weight is influenced by so many factors
How this study found several differences in gut microbiomes between people who lost weight and those who did not
A few tips on how to nurture a healthy gut microbiome (more clinical research is needed before we can develop or recommend probiotics for weight loss)

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Price: US$37

Easy-to-understand study summary with some practical strategies and tips for your clients

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Customizable health study summary with practical tips

Release the pressure to create new health content every week and share study summaries and tips with your email subscribers and/or social media followers

Price: US$37

Related topics: Gut microbiome, weight, nutrition

Backgrounder articles: Links to 3 backgrounder articles

Study design: Participants enrolled into a year-long behavioural coaching program to try to help them lose weight. They provided stool samples and other metrics (e.g., blood samples). The final sub-cohort ended up with 15 participants who lost the most weight and 10 who did not lose weight. The microbiomes of these two groups were compared.

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Click to view the reference for this Health scoop

Diener, C., Qin, S., Zhou, Y., Patwardhan, S., Tang, L., Lovejoy, J. C., Magis, A. T., Price, N. D., Hood, L., & Gibbons, S. M. (2021). Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans. mSystems, 6(5), e0096421. https://doi.org/10.1128/mSystems.00964-21
https://journals.asm.org/doi/10.1128/mSystems.00964-21
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547453/

About the study (these details aren’t included in the client/patient-friendly Scoop, it’s for your info as a research-based health professional):

Microbe = one microscopic organism, like a bacterium, or yeast
Microbiota = a community of different microbes living together
Microbiome = the genes included in a microbiota
Conclusion: “Overall, our results suggest that the microbiota may influence host weight loss responses through variable bacterial growth rates, dietary energy harvest efficiency, and immunomodulation.”
“These findings…may help optimize the weight-loss protocols in future studies.”
The researchers say that it is still too soon to be able to engineer your gut microbiome.
There are currently no probiotics or other treatments that we can recommend, but research is progressing and this may become an option one day in the future.
Note that all studies have limitations. That’s why it’s important to look at multiple studies, giving more weight to the ones that have a better design to answer the questions being asked. For this one, the researchers enrolled participants into a year-long behavioural coaching program to try to help them lose weight. They took stool samples and other metrics (e.g., blood samples). The final sub-cohort ended up with 15 participants who lost the most weight and 10 who did not lose weight.
This means it’s not a randomized control trial as participants were not randomized into an “intervention” or “control/placebo” arm (which would be even better).
Study strength is rated a 5.5/7 according to this chart (better than a cohort, but not as good as an RCT): https://www.compoundchem.com/2015/04/09/scientific-evidence/