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The Microbiome-Gut-Brain Axis: What you need to know for brain and gut health

Until recently, we didn’t know how much our gut and brain interacted. Some people thought that our brains controlled everything we did, consciously and subconsciously.

They were wrong!

Some of us have a sense that there is a connection because we often feel emotions in our gut. For example, when we’re scared we can get a “knot” in our stomach. Or, feeling sad or anxious can affect our appetite and the number of bathroom trips we need to make. Plus, many digestive issues often come with mood issues.

Recent research confirms a gut-brain connection, a.k.a. “axis.” This microbiome-gut-brain axis is stronger and different than we had imagined. And with new technology, we’ve been able to study the gut microbes in a way that was not possible just a few years ago.

Let’s talk about how your gut microbes, your gut itself, your brain, and your mental health are all interconnected and influence each other! Plus, we’ll dive into some “mood foods,” as well as stress reducing activities that can help with gut issues.

The gut and microbiome

The microbiome-gut-brain axis: The observations

The microbiome-gut-brain axis: The nerve connections

The microbiome-gut-brain axis: The biochemical connections

The microbiome-gut-brain axis: The immune and inflammatory connections

Mood foods

What about probiotics?

Reduce stress for your gut

Conclusion

There is a tonne of research digging into these vast and varied interconnections between our gut and our brain. The microbiome-gut-brain axis consists of nerves, biochemicals, and the immune system. This axis is a hotbed of research to try to really understand how our “second brain” affects our moods and vice versa.

There are a number of foods that we can feed our gut that can help our moods, and reducing our stress can have a significant impact on several digestive diseases.

The microbiota-gut-brain axis is an active area of research now. Make sure you treat your gut and your brain well.

References

Avetisyan, M., Schill, E. M., & Heuckeroth, R. O. (2015). Building a second brain in the bowel. The Journal of Clinical Investigation, 125(3), 899–907. http://doi.org/10.1172/JCI76307
LINK:  
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362233/

Bonaz, B. (2013). Inflammatory bowel diseases: a dysfunction of brain-gut interactions? Minerva Gastroenterol Dietol, 59(3):241-59.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/23867945

Bonaz, B., Bazin, T., & Pellissier, S. (2018). The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis. Frontiers in Neuroscience, 12, 49. http://doi.org/10.3389/fnins.2018.00049
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808284/

Brzozowski, B., Mazur-Bialy, A., Pajdo, R., Kwiecien, S., Bilski, J., Zwolinska-Wcislo, M., … Brzozowski, T. (2016). Mechanisms by which Stress Affects the Experimental and Clinical Inflammatory Bowel Disease (IBD): Role of Brain-Gut Axis. Current Neuropharmacology, 14(8), 892–900. http://doi.org/10.2174/1570159X14666160404124127
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333596/

Burokas, A., Moloney, R.D., Dinan, T.G. & Cryan, J.F. (2015). Microbiota regulation of the Mammalian gut-brain axis. Adv Appl Microbiol, 91:1-62. doi: 10.1016/bs.aambs.2015.02.001.
LINK:  
https://www.ncbi.nlm.nih.gov/pubmed/25911232

Carabotti, M., Scirocco, A., Maselli, M. A., & Severi, C. (2015). The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology : Quarterly Publication of the Hellenic Society of Gastroenterology, 28(2), 203–209.
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/

Dash, S. R., O’Neil, A., & Jacka, F. N. (2016). Diet and Common Mental Disorders: The Imperative to Translate Evidence into Action. Frontiers in Public Health, 4, 81. http://doi.org/10.3389/fpubh.2016.00081
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850164/

Dinan, T. G., & Cryan, J. F. (2016). Mood by microbe: towards clinical translation. Genome Medicine, 8, 36. http://doi.org/10.1186/s13073-016-0292-1
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822287/

Eriksson, E. M., Andrén, K. I., Kurlberg, G. K., & Eriksson, H. T. (2015). Aspects of the non-pharmacological treatment of irritable bowel syndrome. World Journal of Gastroenterology : WJG, 21(40), 11439–11449. http://doi.org/10.3748/wjg.v21.i40.11439
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616219/

Furness, J.B., Callaghan, B.P., Rivera, L.R. & Cho, H.J. (2014). The enteric nervous system and gastrointestinal innervation: integrated local and central control. Adv Exp Med Biol, 817:39-71. doi: 10.1007/978-1-4939-0897-4_3.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/24997029

Gao, J., Xu, K., Liu, H., Liu, G., Bai, M., Peng, C., … Yin, Y. (2018). Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism. Frontiers in Cellular and Infection Microbiology, 8, 13. http://doi.org/10.3389/fcimb.2018.00013
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808205/

Jiang, H., Ling, Z., Zhang, Y., Mao, H., Ma, Z., Yin, Y., Wang, W., Tang, W., Tan, Z., Shi, J., Li, L. & Ruan, B. (2015). Altered fecal microbiota composition in patients with major depressive disorder. Brain Behav Immun, 48:186-94. doi: 10.1016/j.bbi.2015.03.016.
LINK:  https://www.sciencedirect.com/science/article/pii/S0889159115001105?via%3Dihub

Johns Hopkins Medicine. The brain-gut connection. Accessed March 7, 2018.
LINK:  http://www.hopkinsmedicine.org/health/healthy_aging/healthy_body/the-brain-gut-connection

Knight, R., Callewaert, C., Marotz, C., Hyde, E.R., Debelius, J.W., McDonald, D. & Sogin, M.L. (2017). The Microbiome and Human Biology. Annu Rev Genomics Hum Genet, 18:65-86. doi:10.1146/annurev-genom-083115-022438.
LINK:  http://www.annualreviews.org/doi/full/10.1146/annurev-genom-083115-022438?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

LeBlanc, J. G., Chain, F., Martín, R., Bermúdez-Humarán, L. G., Courau, S., & Langella, P. (2017). Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria. Microbial Cell Factories, 16, 79. http://doi.org/10.1186/s12934-017-0691-z
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423028/

Lerner, A., Neidhöfer, S., & Matthias, T. (2017). The Gut Microbiome Feelings of the Brain: A Perspective for Non-Microbiologists. Microorganisms, 5(4), 66. http://doi.org/10.3390/microorganisms5040066 
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748575/

Ma, N., Guo, P., Zhang, J., He, T., Kim, S. W., Zhang, G., & Ma, X. (2018). Nutrients Mediate Intestinal Bacteria–Mucosal Immune Crosstalk. Frontiers in Immunology, 9, 5. http://doi.org/10.3389/fimmu.2018.00005 
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787545/

McKean, J., Naug, H., Nikbakht, E., Amiet, B. & Colson, N. (2017). Probiotics and Subclinical Psychological Symptoms in Healthy Participants: A Systematic Review and Meta-Analysis. J Altern Complement Med, 23(4):249-258. doi: 10.1089/acm.2016.0023.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/27841940

Opie, R.S., O’Neil, A., Itsiopoulos, C. & Jacka, F.N. (2015). The impact of whole-of-diet interventions on depression and anxiety: a systematic review of randomised controlled trials. Public Health Nutr, 18(11):2074-93. doi: 10.1017/S1368980014002614.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/25465596/

Pellissier, S. & Bonaz, B. (2017). The Place of Stress and Emotions in the Irritable Bowel Syndrome. Vitam Horm. 2017;103:327-354. doi: 10.1016/bs.vh.2016.09.005.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/28061975

Pirbaglou, M., Katz, J., de Souza, R.J., Stearns, J.C., Motamed, M. & Ritvo, P. (2016). Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials. Nutr Res, 36(9):889-898. doi: 10.1016/j.nutres.2016.06.009.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/27632908

Rogers, G. B., Keating, D. J., Young, R. L., Wong, M.-L., Licinio, J., & Wesselingh, S. (2016). From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways. Molecular Psychiatry, 21(6), 738–748. http://doi.org/10.1038/mp.2016.50 
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879184/

Science Daily. Sympathetic Nervous System. Accessed March 7, 2018.
LINK:  https://www.sciencedaily.com/terms/sympathetic_nervous_system.htm

Sender, R., Fuchs, S. & Milo, R. (2016). Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLoS Biol 14(8): e1002533. https://doi.org/10.1371/journal.pbio.1002533
LINK:  http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002533

TILLISCH, K., LABUS, J., KILPATRICK, L., JIANG, Z., STAINS, J., EBRAT, B., … MAYER, E. A. (2013). Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity. Gastroenterology, 144(7), 10.1053/j.gastro.2013.02.043. http://doi.org/10.1053/j.gastro.2013.02.043 
LINK:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839572/

UpToDate: Chron Disease. Accessed March 9, 2018.
L
INK:  https://www.uptodate.com/contents/crohn-disease-beyond-the-basics

UpToDate: Irritable Bowel Syndrome. Accessed March 9, 2018.
LINK:  https://www.uptodate.com/contents/irritable-bowel-syndrome-beyond-the-basics

Wang, W., Wang, F., Fan, F., Sedas, A.C. & Wang, J. (2017). Mind-Body Interventions for Irritable Bowel Syndrome Patients in the Chinese Population: a Systematic Review and Meta-Analysis. Int J Behav Med, 24(2):191-204. doi: 10.1007/s12529-016-9589-0.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/27646279

Zheng, P., Zeng, B., Zhou, C., Liu, M., Fang, Z., Xu, X., Zeng, L., Chen, J., Fan, S., Du, X., Zhang, X., Yang, D., Yang, Y., Meng, H., Li, W., Melgiri, N.D., Licinio, J., Wei, H. & Xie, P. (2016). Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism. Mol Psychiatry, 21(6):786-96. doi: 10.1038/mp.2016.44.
LINK:  https://www.ncbi.nlm.nih.gov/pubmed/27067014?dopt=Abstract